The playfield is viewed from above as a vertical bottle containing colored viruses. Capsules fall from the top, and the player moves and rotates them before they settle.

The objective is to remove every virus. Matching three or more adjacent segments of the same color horizontally or vertically clears them, while unsupported capsule halves can separate and fall. The player can choose virus levels and speed, and the game ends when the bottle becomes blocked.

Plan around the lowest viruses instead of clearing only the most visible matches. Use capsule halves to create several potential matches, and avoid building tall, uneven stacks that restrict later placements.

At higher speeds, prioritize safe landings and look for chain reactions. Removing a supporting segment can make separated pieces fall and create useful follow-up matches.