The game uses an isometric perspective for exploring settlements, ruins, caves, and wilderness. The main objective is to recover a water-chip and later investigate a growing mutant threat, while optional quests allow different approaches and outcomes.

Combat is turn-based. Action points govern movement, attacks, equipment use, and other actions. Outside combat, the player creates a character with the SPECIAL system, develops skills, gathers equipment, speaks with non-player characters, and can recruit companions. Reputation, dialogue choices, and quest decisions influence available solutions and parts of the ending.

Build a balanced character rather than specializing in too many skills. Speech, one combat skill, and a practical utility skill such as Lockpick or Science provide useful options.

Manage action points carefully during combat, use cover and distance when possible, and save before major conversations or unexplored locations. Explore optional areas, recruit suitable companions, and pay attention to time-sensitive objectives.