The game uses a side-scrolling action perspective. Players guide a team of Marvel heroes through combat-focused stages, defeating enemies, completing objectives, and advancing the story.

A small group of heroes can be assembled for each mission, with the player switching between available characters during play. Battles reward movement, normal attacks, special abilities, and use of character-specific powers. Progression comes from clearing stages and improving the effectiveness of the selected team.

Learn enemy attack patterns before committing to extended combos, especially in crowded rooms. Keep the active hero moving and switch characters when a matchup or special ability is more useful.

Use each hero according to their strengths: agile characters can evade pressure, while durable melee fighters can hold enemy attention. Explore stages for useful pickups and avoid spending special abilities when ordinary attacks are sufficient.