The game uses a side-view perspective and places Spider-Man in hazardous, screen-based areas. The main objective is to move through the stages, overcome enemies and obstacles, and advance toward the rescue of Mary Jane.

Spider-Man can move, jump, climb, fight, and use web attacks where the game permits. Progress depends on navigating platforms and passages while dealing with enemies and environmental hazards. The DOS release is a single-player adventure rather than a multiplayer title.

Treat each area as a navigation and timing challenge rather than rushing forward. Use Spider-Man’s web ability to handle appropriate obstacles or enemies, and watch enemy movement before committing to a jump or attack.

Explore the edges of screens and passages carefully. Progress is safest when you learn the layout, avoid unnecessary contact damage, and keep a reliable route back through areas you have already cleared.