The player views the expedition through menu-driven screens and illustrated scenes rather than direct character movement. The main objective is to reach Quito with the expedition intact while managing food, equipment, health, and travel decisions.

Players choose routes, respond to river conditions, stop at settlements, and take part in fishing, hunting, trading, and information-gathering activities. Progress depends on supplies and decisions; poor choices can delay the journey or end the expedition.

Buy and protect enough food and equipment for difficult stretches, but avoid spending all money early. Read descriptions of river conditions and settlements before choosing a route. Use fishing, hunting, and trading to replace supplies when possible, and prioritize safe progress over unnecessary detours.