The game uses a side-view perspective. Spider-Man advances through separately structured stages, defeating street-level enemies, navigating platforms, climbing walls, and confronting bosses based on characters from the comics.

Movement and combat are built around jumping, punches, kicks, web-based attacks, and Spider-Man’s ability to move across vertical surfaces. Progression is primarily stage-based rather than experience-driven; completing a level leads to the next area, with boss encounters providing major checkpoints.

Use vertical surfaces to control enemy positioning instead of fighting every opponent in open space. Wall movement can also help you avoid hazards and approach enemies from safer angles.

Conserve health by learning enemy attack timing and by using web attacks when direct combat is risky. Before a boss encounter, clear nearby enemies and identify safe locations for jumping or retreating.