The game uses a two-dimensional side-scrolling perspective. Spider-Man moves through stages, climbs or swings around obstacles, defeats ordinary enemies, and reaches a major villain encounter at the end of a level.

Players must combine platforming with close-range attacks and web-based abilities. Progression is stage-based, with different environments and opponents introducing new hazards. The main experience is a single-player campaign; no separate multiplayer mode is documented for this version.

Learn the timing of Spider-Man’s jump and web attacks before rushing into unfamiliar rooms. Use distance and elevated positions whenever possible, because many enemies are easier to handle when they cannot surround Spider-Man.

Against bosses, observe the attack pattern first and strike only after an opening. Preserve health by avoiding unnecessary contact with regular enemies, and treat each stage as a sequence of short positioning challenges rather than a continuous attack.